Arimidex 1 mg (28 Tablets) | Anastrozole Breast Cancer Treatment | AstraZeneca
Arimidex 1 mg is a critical prescription medication containing the active ingredient Anastrozole. It is a leading first-line oral treatment for hormone receptor-positive (HR+) breast cancer in postmenopausal women. This 28-tablet package from AstraZeneca is a potent aromatase inhibitor (AI) designed to significantly reduce estrogen levels in the body.
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Arimidex 1 mg Anastrozole (28 Tablets)
Arimidex 1 mg is a critical prescription medication containing the active ingredient Anastrozole. It is a leading first-line oral treatment for hormone receptor-positive (HR+) breast cancer in postmenopausal women. This 28-tablet package from AstraZeneca is a potent aromatase inhibitor (AI) designed to significantly reduce estrogen levels in the body.
Product Overview: Arimidex 1 mg (Anastrozole)
Arimidex 1 mg (Anastrozole) is a powerful, non-steroidal aromatase inhibitor. Its primary, approved medical function is as an “adjuvant” therapy (following surgery or other treatments) for postmenopausal women diagnosed with hormone-sensitive breast cancer.
By lowering the body’s circulating estrogen, Arimidex helps to “starve” cancer cells that rely on estrogen to grow, thereby reducing the risk of cancer recurrence.
Outside of its primary medical use, Anastrozole is also used “off-label” by men to manage estrogen levels, often as part of a Post-Cycle Therapy (PCT) protocol or during an anabolic steroid cycle to prevent estrogenic side effects like gynecomastia.
How Does Arimidex 1 mg (Anastrozole) Work?
The active ingredient, Anastrozole, works by blocking a key enzyme in the body called aromatase.
- In Postmenopausal Women: The aromatase enzyme is the primary pathway for producing estrogen (by converting androgens into estrogen in fatty tissues). By inhibiting this enzyme, Arimidex effectively stops estrogen production, significantly lowering estrogen levels.
- In Men (Off-Label Use): This same mechanism prevents the conversion (aromatization) of testosterone into estrogen, thereby controlling estrogen-related side effects.
Key Product Details
| Feature | Detail |
| Brand: | Arimidex |
| Manufacturer: | AstraZeneca |
| Active Ingredient: | Anastrozole |
| Dosage Strength: | 1 mg |
| Form: | Film-coated tablet |
| Package Size: | 28 tablets (Approx. 1-month supply) |
| Indication: | HR+ Breast Cancer (Postmenopausal); Off-label: PCT |
Dosage and Administration
The dosage for Arimidex 1 mg depends entirely on the reason for its use.
- For Breast Cancer: The standard, approved dose is one 1 mg tablet taken once daily.
- For Male Off-Label Use (PCT/Hormone Control): Doses vary widely and are not medically standardized. They are often much lower than the clinical dose (e.g., 0.5 mg to 1 mg, taken every 2-3 days).
Important: This is a prescription-only medication. You must follow the exact instructions provided by your oncologist or healthcare provider.
Frequently Asked Questions (FAQ) about Arimidex 1 mg
What is the difference between Arimidex (an AI) and Klomen/Nolvadex (a SERM)?
They work in completely different ways.
- Arimidex (Aromatase Inhibitor – AI): Stops the production of estrogen in the body.
- Klomen/Nolvadex (SERMs): Do not stop estrogen production. They block estrogen from attaching to specific receptors (e.g., in breast tissue).
What are the common side effects of Arimidex 1 mg?
Because it drastically lowers estrogen, the most common side effects are similar to menopause symptoms. These include hot flashes, joint pain (arthralgia), weakness, fatigue, and mood changes.
Is Arimidex 1 mg safe for men?
Arimidex is not approved by regulatory bodies (like the FDA or EMA) for use in men. Off-label use carries risks, as lowering estrogen too much can lead to negative side effects, including low libido, depression, fatigue, and unhealthy cholesterol levels.
Can Arimidex cause bone loss?
Yes. This is one of the most significant risks. By lowering estrogen, Anastrozole can cause a significant decrease in bone mineral density over time, increasing the risk of osteoporosis and fractures. Your doctor will monitor your bone health.
Important Safety Information
Warning for Women: Arimidex (Anastrozole) is intended for postmenopausal women ONLY. It must not be taken by women who are premenopausal. It is contraindicated in pregnancy as it can cause serious fetal harm.
Before taking Arimidex 1 mg, tell your doctor about your full medical history, especially:
- If you have a history of osteoporosis or poor bone density.
- If you have a history of high cholesterol.
- If you have severe liver or kidney disease.
- If you have a history of blood clots or stroke.
Do not take Arimidex if you are also taking Tamoxifen (Nolvadex) or any medications that contain estrogen (like Hormone Replacement Therapy), as they can interfere with its action.
Disclaimer: This content is for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Arimidex (Anastrozole) is a potent prescription medication. Always consult with your oncologist or qualified healthcare provider.

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