Nebido 1000 mg / 4 ml (Testosterone Undecanoate) Injection

Nebido is a long-acting, intramuscular injectable solution used for Testosterone Replacement Therapy (TRT). It is prescribed for men with clinically diagnosed low testosterone levels (male hypogonadism). This single 4 ml ampoule contains 1000 mg of the active ingredient Testosterone Undecanoate and is manufactured by Bayer.

Product Overview: Nebido for Long-Acting TRT

Nebido (Testosterone Undecanoate) is a powerful, long-acting solution for restoring testosterone levels in men with hypogonadism. Unlike daily gels, patches, or short-acting injections, Nebido is administered in long intervals (typically every 10-14 weeks), providing stable and consistent testosterone levels without daily dosing.

This treatment is designed to alleviate the symptoms of low testosterone, which can include low libido, erectile dysfunction, fatigue, depressed mood, and loss of muscle mass. Nebido works by replenishing the body’s primary male hormone, helping to restore normal physiological function.

How Does Nebido (Testosterone Undecanoate) Work?

The active ingredient, Testosterone Undecanoate, is suspended in a castor oil solution. When injected deep into a muscle (intramuscularly), this solution forms a “depot” (a reservoir) in the muscle tissue.

From this depot, the body’s own enzymes slowly cleave the undecanoate ester, gradually releasing testosterone into the bloodstream over several weeks. This slow-release mechanism is what allows Nebido to be effective for 10 to 14 weeks from a single injection, maintaining testosterone levels in the normal physiological range.

Key Product Details

Dosage and Administration

Nebido is a prescription-only medication that must be administered by a healthcare professional (e.g., a doctor or nurse). It is not intended for self-administration.

• Route: Deep intramuscular (IM) injection.
• Dosing: The standard dose is one 1000 mg (4 ml) injection.
• Frequency: The injection is typically repeated every 10 to 14 weeks. Your doctor will determine the exact injection interval based on your testosterone blood levels.

Important: The injection must be administered very slowly to avoid a rare but serious complication called Pulmonary Oil Microembolism (POME), where oil droplets enter the bloodstream.

Frequently Asked Questions (FAQ) about Nebido

How long does one Nebido injection last?

A single 1000 mg injection of Nebido is designed to last for a long period, typically between 10 and 14 weeks, before the next dose is required.

How is Nebido different from testosterone gels or patches?

Nebido is a long-acting injection, meaning you only need an injection every 10-14 weeks. Gels and patches are “transdermal” and must be applied every day. Nebido provides very stable hormone levels and eliminates the risk of transferring the testosterone to others (e.g., a partner or child) through skin contact.

How quickly will I feel the effects of Nebido?

Effects vary by individual. Some symptoms, like libido and mood, may begin to improve within the first few weeks. Physical changes, such as increases in muscle mass and bone density, take several months.

What are the common side effects of Nebido?

Common side effects can include pain or swelling at the injection site, acne, oily skin, weight gain, and polycythemia (an increase in red blood cell count). Your doctor will monitor your blood work regularly.

Important Safety Information

Nebido (Testosterone Undecanoate) is a powerful hormone and is not suitable for everyone.

Do not use Nebido if you:

• Have or are suspected to have prostate cancer.
• Have or are suspected to have male breast cancer.
• Are allergic to Testosterone Undecanoate or any of the ingredients (like castor oil).

Before starting TRT, your doctor must screen you for these conditions. Your healthcare provider will need to monitor your blood levels (testosterone, red blood cell count, and PSA) regularly during treatment.

Risks: Testosterone therapy can increase the risk of certain conditions, such as polycythemia (high red blood cell count), sleep apnea, and Benign Prostatic Hyperplasia (BPH). It also has the potential for abuse.

Disclaimer: This content is for informational purposes only and is not a substitute for professional medical advice. Nebido is a prescription medication for a diagnosed medical condition. Always consult with a qualified endocrinologist or healthcare provider.